Plexus Process System

A Modular, Engineer-to-Order Platform for Behavior-Critical Bioprocessing

The Plexus™ Process System (PPS) is Alphinity’s modular, engineer-to-order bioprocessing platform, designed for applications where flow behavior, pressure stability, and system integration directly impact manufacturing outcomes.

Rather than a fixed skid, PPS provides a configurable system architecture that integrates seamlessly into downstream operations and can scale from development through GMP manufacturing.

Why PPS Exists

As bioprocesses evolve, many manufacturing challenges are no longer chemical — they are physical and mechanical.

Teams increasingly face flow instability, pressure transients, and system architectures that struggle to scale cleanly. Traditional catalogue-based systems often force processes to adapt to equipment, leading to workarounds, conservative operating limits, and repeated redesign.

PPS is designed to address these challenges at the system level, embedding predictable flow behavior, pressure control, and scalability from the outset.

What PPS Enables

Depending on configuration, the Plexus Process System can support:

• Process feed and conditioning

• Inline mixing and blending

• Buffer preparation and dilution

• Viral inactivation feed and mixing architectures

• Integrated, automation-ready process workflows

Each PPS configuration is tailored to the application, control strategy, and

scale intent — not constrained by fixed catalogue layouts.

Who PPS Is Designed For

PPS is best suited for teams operating behavior-critical processes, including:

• Fragile or shear- and cavitation-sensitive modalities

• Viscous or complex process streams

• Pressure-sensitive filtration and TFF operations

• Automated or semi-automated manufacturing environments

• Platforms expected to scale without repeated redesign

Engineer-to-Order by Design

Every Plexus Process System follows Alphinity’s engineer-to-order approach, ensuring systems are designed around the process — not adapted after the fact.

This enables PPS to evolve with process requirements while maintaining physical process continuity from PD through GMP.

Build the System Your Process Actually Needs

The Plexus Process System provides a flexible, precision-engineered foundation for modern bioprocessing.