FAQs

VannX™ FAQ- Technical

What is VannX™?

VannX™ is a single-use motorized diaphragm valve for sterile fluid control in biopharmaceutical processes.

  • 1000's-step (and micro stepping) motorized actuation enables precise modulation (±0.05 bar).

  • Compact, modular geometry reduces holdup volume and supports integration into valve blocks (Vannefold™).

  • Designed as a drop-in replacement for existing tubing and manifold assemblies.

How is VannX™ different?

  • Fully single-use: Unlike competitors, the actuator is also disposable → no cleaning validation.

  • Compact footprint: Replaces bulky pneumatic/motorized housings with lightweight, low-profile blocks.

  • Precision: 1000’s-step control vs pneumatic actuation or limited electronic control.

  • 24V DC: No compressed air infrastructure.

  • Pharma 4.0 Ready: Encoder feedback + IP65 design for integration with modern automation platforms.

What are the technical specifications?

  • Sizes: 1/8” – 1” (DN 3–25)

  • Pressure range: -1.0 bar (vacuum) to 6.0 bar

  • Travel speed: 3 mm/s

  • Materials: PP body + TPE diaphragm (resists swelling/fusing)

  • Ingress protection: IP65

  • Electrical: 24 V DC, bipolar stepper with encoder, M12 connectors

  • Environment: 4°C to 40°C; manufactured in ISO Class 7 cleanroom

What compliance and validation standards does it meet?

  • FDA compliant

  • USP Class VI for biocompatibility

  • BSE/TSE free

  • Validated for 100,000 switching cycles

  • Meets global single-use bioprocessing component standards

  • Assembled in ISO Class 7 sterility requirements

How does the drop-in compatibility work?

  • Connection options: Hose barb or clamp (ASME-BPE)

  • Electrical interface: Standard M12 connectors (5-pin / 8-pin)

  • System integration: Works with standard skid control systems, no reengineering required

  • Modularity: Can be used standalone or in Vannefold™ valve clusters to reduce footprint and dead legs.

What are the process benefits for engineers?

  • Yield: Optimized internal geometry for fluid removal and product recovery.

  • Shear protection: Gentle actuation protects sensitive cell cultures and viral vectors.

  • Cleanroom efficiency: Single-use design avoids cleaning/sterilization steps, freeing engineering resources.

  • Validation simplification: Reduced risk of cross-contamination.

Typical Applications

  • Cell & Gene Therapy: Precision flow control for shear-sensitive cells.

  • Monoclonal Antibodies (mAbs): Reduce product loss in high-value runs.

  • Biosimilars: Lower cost of goods via reduced waste.

  • Vaccines & Viral Vectors: Scalable, sterile manufacturing.

How does it impact system economics?

  • Changeovers: Up to 50% faster vs pneumatic systems.

  • Product yield: Significant recovery improvement from reduced dead volume.

  • Operating cost: Lower energy (24V vs air compressors)

VannX™ FAQ- Commercial

What is VannX™?

VannX™ is a single-use motorized diaphragm valve for sterile fluid control in biopharmaceutical processes.

  • 1000's-step (and micro stepping) motorized actuation enables precise modulation (±0.05 bar).

  • Compact, modular geometry reduces holdup volume and supports integration into valve blocks (Vannefold™).

  • Designed as a drop-in replacement for existing tubing and manifold assemblies.

How is VannX™ different?

  • Compact footprint: Replaces bulky pneumatic/motorized housings with lightweight, low-profile blocks.

  • Precision: 1000's-step control vs pneumatic actuation or limited electronic control.

  • 24V DC: No compressed air infrastructure.

  • Pharma 4.0 Ready: Encoder feedback + IP65 design for integration with modern automation platforms.

Why VannX™ over other valves?

Because it’s the first valve designed for today’s biopharma reality — not yesterday’s.

  • Legacy pneumatic valves need bulky air systems.

  • Motorized options are oversized and still reuse actuators.

VannX™ is compact, fully single-use, automation-ready, and drop-in compatible with your existing skids.

What business benefits will I see?

  • More Batches, Faster: more runs per year.

  • Less Waste, Higher Yield: Low hold-up design means more product captured.

  • Smaller Footprint: Free up valuable cleanroom space.

  • Direct Savings

Is it easy to adopt?

Yes — VannX™ is a drop-in solution. No reengineering, no retraining, no downtime. Plug into existing single-use assemblies and skids, and you’re running.

Is it compliant?

  • 100% single-use design

  • FDA compliant

  • USP Class VI certified

  • Manufactured in ISO Class 7 cleanroom

✔ Ready for global GMP audits.

Who is VannX™ for?

  • Biopharma manufacturers scaling clinical → commercial

  • CDMOs seeking faster turnaround and more throughput

  • CGT innovators protecting high-value cells and vectors

  • Procurement leaders tasked with reducing cost-of-goods (CoGs)

What’s the bottom line?

VannX™ gives you:

  • More product out

  • More runs per year

  • Less validation overhead

  • Smaller, smarter systems

It’s the valve that pays for itself.