Pinch Valve Series
ARTēVA® is Alphinity's family of stainless steel pinch valves for bioprocessing. Three actuation options — electric, pneumatic, and manual — built on one proven 316L stainless steel pinch head. Single-use tubing. Reusable mechanism. Over 30 years of sanitary valve manufacturing experience.
Three Actuation Options
Every ARTēVA® valve shares the same 316L stainless steel encapsulated pinch head and single-use tubing compatibility. Choose your actuation based on your process requirements — electric precision, pneumatic speed, or manual simplicity.
Electrically actuated · Stepper motor control
Best for: Automated skids, perfusion, filtration control, media/buffer transfer
Pneumatically actuated · Fast uniform closure
Best for: High-throughput commercial production lines with existing pneumatic infrastructure
Manual actuation · Tool-free operation
Best for: Lab-scale development, benchtop setups, mobile carts, small-scale sterile operations
Core Design
Every ARTēVA® variant shares the same fundamental architecture — a reusable 316L stainless steel encapsulated pinch head with single-use tubing. The actuation changes. The reliability doesn't.
Encapsulated, hygienic, corrosion-resistant, and autoclavable. Built for repeated use, cleaning, and long-term performance in demanding bioprocess environments.
Consistent sealing geometry across thousands of cycles. No variation, no guesswork — the same reliable pinch every time.
Works with silicone, TPE, braided and reinforced single-use tubing from ¼″ to 1″ ID. No proprietary consumables, no vendor lock-in.
Single-use tubing swaps in seconds without tools. Sterility maintained. Operator time minimised. No cleaning validation required.
Clear operator feedback at a glance. Know the valve state without instrumentation — essential for manual operations and visual process checks.
Produced in the United States by Alphinity's stainless steel valve division — over 30 years of experience designing and manufacturing sanitary bioprocessing components.
Where ARTēVA® works
ARTēVA® valves are used across upstream and downstream bioprocessing — anywhere a reliable, hygienic pinch valve is needed with single-use tubing compatibility.
Media and buffer transfer, cell culture feed lines, perfusion circuits, and bioreactor inlet/outlet control. The reusable pinch mechanism handles repeated cycling with consistent compression.
Filtration and chromatography systems, harvest and collection paths, viral inactivation hold steps, and final fill workflows. Single-use tubing eliminates cross-contamination between batches.
Sampling points, bypass operations, and diversion paths where quick, reliable switching is needed without contaminating the main product stream.
Process development, screening, and small-scale sterile operations. The Manual variant requires no infrastructure — just clamp on, connect tubing, and operate.
Valve Selector
From simple manual control to full digital automation — find the variant that fits your application, scale, and infrastructure.
Not sure which variant fits? Talk to an engineer →
Part of the Alphinity Platform
ARTēVA® pinch valves integrate directly into systems built around PIXER® pumps and VannX™ diaphragm valves — covering every flow control requirement from gentle product transfer to precision pressure control.
Pump Technology
Ultra-low shear positive displacement pumping for fragile biologics and viscous formulations. Pairs with ARTēVA® for complete flow path control.
Precision Valve Technology
±0.3 PSI proportional pressure control. 24V DC electric, no compressed air. Complements ARTēVA® where precision TMP control is required.
Integrated Systems
ARTēVA®, PIXER®, and VannX™ combined into fully integrated, automation-ready bioprocessing systems. Built around your process.
Why ARTēVA®
The stainless steel pinch head is built to last thousands of cycles. The tubing is disposable. That combination delivers the sterility assurance of single-use with the cost efficiency of a reusable instrument — without compromise.
Fully disposable pinch valves replace the entire mechanism with each batch, driving high consumable costs over time. ARTēVA®'s reusable stainless steel head significantly reduces cost of ownership — only the tubing is replaced.
Yes. The 316L stainless steel pinch head is autoclavable. The single-use tubing is replaced between runs, maintaining sterility without cleaning validation.
ARTēVA® is compatible with ¼″ to 1″ ID tubing across silicone, TPE, braided, and reinforced formats. No proprietary tubing required.
ARTēVA® is manufactured in the United States by Alphinity's stainless steel valve division — over 30 years of experience producing sanitary bioprocessing components.
Get Started
Talk to our engineers about your application — tubing size, cycle frequency, actuation preference, and integration requirements. We'll specify the right variant.